Childhood acute lymphoblastic leukaemia in relation to population mixing around the time of birth in South Hungary.
Pediatr Blood Cancer
; 47(7): 944-8, 2006 Dec.
Article
em En
| MEDLINE
| ID: mdl-16421899
ABSTRACT
In a retrospective epidemiological study of 481,984 live births in South Hungary, we investigated whether higher levels of population mixing around the time of birth is a risk factor for acute lymphoblastic leukemia (ALL) under age 5 years. Poisson regression was used to investigate the relationship between risk of ALL and the population-mixing index based on the number of incomers in each county district for each year, standardized to have a range of 0-1. Among all children, the risk of ALL increased significantly with increasing population mixing around the time of birth (trend across the range of 0-1 RR = 2.1 95% CI 1.02-4.44). This effect was more marked for boys (RR = 3.1 95% CI 1.13-8.51), which supports a sex-specific effect of exposures on risk of ALL.
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Base de dados:
MEDLINE
Assunto principal:
Leucemia-Linfoma Linfoblástico de Células Precursoras
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Newborn
País como assunto:
Europa
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article