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Gene targeting in plants: fingers on the move.
Kumar, Sandeep; Allen, George C; Thompson, William F.
Afiliação
  • Kumar S; Department of Botany, North Carolina State University, Raleigh, NC 27695-7612, USA. skumar3@unity.ncsu.edu
Trends Plant Sci ; 11(4): 159-61, 2006 Apr.
Article em En | MEDLINE | ID: mdl-16530459
Zinc-finger endonucleases (ZFNs) make targeted double-stranded breaks in genomic DNA and, thus, stimulate recombination and repair processes at specific sites. ZFNs can now be harnessed to stimulate homologous recombination and gene targeting in plants, which represents a major step towards modifying the plant genome more precisely. ZFN-mediated gene targeting is likely to become a powerful tool for genome research and genetic engineering.
Assuntos
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Base de dados: MEDLINE Assunto principal: Plantas / Dedos de Zinco / Marcação de Genes / Endodesoxirribonucleases Idioma: En Ano de publicação: 2006 Tipo de documento: Article
Buscar no Google
Base de dados: MEDLINE Assunto principal: Plantas / Dedos de Zinco / Marcação de Genes / Endodesoxirribonucleases Idioma: En Ano de publicação: 2006 Tipo de documento: Article