Monte Carlo optimisation of a BNCT facility for treating brain gliomas at the TAPIRO reactor.
Radiat Prot Dosimetry
; 116(1-4 Pt 2): 475-81, 2005.
Article
em En
| MEDLINE
| ID: mdl-16604681
ABSTRACT
An epithermal boron neutron capture therapy facility for treating brain gliomas is currently under construction at the 5 kW fast-flux reactor TAPIRO located at ENEA, Casaccia, near Rome. In this work, the sensitivity of the results to the boron concentrations in healthy tissue and tumour is investigated and the change in beam quality on modifying the moderator thickness (within design limits) is studied. The Monte Carlo codes MCNP and MCNPX were used together with the DSA in-house variance reduction patch. Both usual free beam parameters and the in-phantom treatment planning figures-of-merit have been calculated in a realistic anthropomorphic phantom ('ADAM').
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Base de dados:
MEDLINE
Assunto principal:
Radiometria
/
Planejamento da Radioterapia Assistida por Computador
/
Neoplasias Encefálicas
/
Terapia por Captura de Nêutron de Boro
/
Glioma
/
Modelos Biológicos
Tipo de estudo:
Health_economic_evaluation
Limite:
Humans
País como assunto:
Europa
Idioma:
En
Ano de publicação:
2005
Tipo de documento:
Article