[Evaluation on the visual inspection with Lugol's iodine in cervical cancer screening program].
Zhonghua Liu Xing Bing Xue Za Zhi
; 27(1): 15-8, 2006 Jan.
Article
em Zh
| MEDLINE
| ID: mdl-16737565
OBJECTIVE: To evaluate visual inspection with Lugol's iodine (VILI) in cervical cancer screening program and to provide evidence for designing a cervical cancer screening algorithm in high risk areas of existing low-resource settings to reduce the incidence and mortality of cervical cancer. METHODS: Women in Yangcheng county, Shanxi province were screened with VILI, colposcopy, liquid-based cytology test and human papilloma virus (HPV) DNA test. The efficacy of different screening tests was compared by Youden's index based on the pathology as the gold standard. RESULTS: In the population being screened, the mean age was 40.80 +/- 10.75 years old. Based on pathological findings, 4.35% (32/735) of the subjects had >or= CIN (cervical intraepithelial neoplasia) II. The sensitivity and specificity for the VILI test (>or= positive) were 53.13 and 82.19, while 56.25 and 79.09 were for colposcopy (>or= low grade dysplasia) respectively. Comparing by the Youden's indexs, there was no statistically significant difference (P > 0.05) between VILI and colposcopy. However, statistical significant difference (P < 0.05) was found between VILI and liquid-based cytology test and HPV DNA test. In addition, there was no statistically significant difference (P > 0.05) found between the experienced doctors and the newly-trained doctors working in the field station. CONCLUSION: With low sensitivity when using microscope but low cost of equipments, VILI can be one of the primary screening tests in China's rural area with low-resource settings if the screening frequency is to be increased.
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Base de dados:
MEDLINE
Assunto principal:
Displasia do Colo do Útero
/
Neoplasias do Colo do Útero
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Detecção Precoce de Câncer
/
Iodetos
Tipo de estudo:
Diagnostic_studies
/
Evaluation_studies
/
Incidence_studies
/
Prognostic_studies
/
Screening_studies
Limite:
Adult
/
Female
/
Humans
País como assunto:
Asia
Idioma:
Zh
Ano de publicação:
2006
Tipo de documento:
Article