A randomized trial to evaluate 2 hours of daily patching for strabismic and anisometropic amblyopia in children.
Ophthalmology
; 113(6): 904-12, 2006 Jun.
Article
em En
| MEDLINE
| ID: mdl-16751033
ABSTRACT
OBJECTIVE:
To compare 2 hours of daily patching (combined with 1 hour of concurrent near visual activities) with a control group of spectacle wear alone (if needed) for treatment of moderate to severe amblyopia in children 3 to 7 years old.DESIGN:
Prospective randomized multicenter clinical trial (46 sites).PARTICIPANTS:
One hundred eighty children 3 to 7 years old with best-corrected amblyopic-eye visual acuity (VA) of 20/40 to 20/400 associated with strabismus, anisometropia, or both who had worn optimal refractive correction (if needed) for at least 16 weeks or for 2 consecutive visits without improvement. INTERVENTION Randomization either to 2 hours of daily patching with 1 hour of near visual activities or to spectacles alone (if needed). Patients were continued on the randomized treatment (or no treatment) until no further improvement was noted. MAIN OUTCOMEMEASURE:
Best-corrected VA in the amblyopic eye after 5 weeks.RESULTS:
Improvement in VA of the amblyopic eye from baseline to 5 weeks averaged 1.1 lines in the patching group and 0.5 lines in the control group (P = 0.006), and improvement from baseline to best measured VA at any visit averaged 2.2 lines in the patching group and 1.3 lines in the control group (P<0.001).CONCLUSION:
After a period of treatment with spectacles, 2 hours of daily patching combined with 1 hour of near visual activities modestly improves moderate to severe amblyopia in children 3 to 7 years old.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Privação Sensorial
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Anisometropia
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Ambliopia
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Estrabismo
Tipo de estudo:
Clinical_trials
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Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Child
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Child, preschool
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article