Mycoplasma genitalium infection and persistence in a cohort of female sex workers in Nairobi, Kenya.
Sex Transm Dis
; 34(5): 274-9, 2007 May.
Article
em En
| MEDLINE
| ID: mdl-16940898
ABSTRACT
OBJECTIVE:
The objective of this study was to assess the risk factors for and persistence of Mycoplasma genitalium (MG) in a highly exposed female population in Kenya. STUDYDESIGN:
Two hundred fifty-eight sex workers in Nairobi, Kenya, 18 to 35 years of age, were enrolled. Every 2 months, cervical samples were collected for MG, Chlamydia trachomatis (CT), and Neisseria gonorrhoeae (GC) testing by polymerase chain reaction.RESULTS:
At enrollment, 16% were infected with MG. Seventy-seven subjects acquired 107 MG infections, giving an incidence of 22.7 per 100 women-years. Incident CT (adjusted hazard ratio [HR] = 2.4; 95% confidence interval [CI] = 1.5-4.0), GC (HR = 2.0; 95% CI = 1.2-3.5), and HIV infection (adjusted HR = 2.2; 95% CI = 1.3-3.7) were associated with an increased risk of MG. Seventeen percent, 9%, and 21% of MG infections persisted 3, 5, and >or=7 months, respectively.CONCLUSION:
The high incidence of MG, greater than that for both CT (14.0%) and GC (8%), association with common sexually transmitted infection risk factors, and persistence in the female genital tract supports its role as a common sexually transmitted infection in Kenyan women.
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Base de dados:
MEDLINE
Assunto principal:
Trabalho Sexual
/
Infecções Sexualmente Transmissíveis
/
Chlamydia trachomatis
/
Mycoplasma genitalium
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Female
/
Humans
País como assunto:
Africa
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article