Voxelwise correlational analyses of white matter integrity in multiple cognitive domains in schizophrenia.
Am J Psychiatry
; 163(11): 2008-10, 2006 Nov.
Article
em En
| MEDLINE
| ID: mdl-17074956
ABSTRACT
Patients with schizophrenia show deficits in several neurocognitive domains. However, the relationship between white matter integrity and performance in these domains is poorly understood. The authors conducted neurocognitive testing and diffusion tensor imaging in 25 patients with schizophrenia. Performance was examined for tests of verbal declarative memory, attention, and executive function. Relationships between fractional anisotropy and cognitive performance were examined by using voxelwise correlational analyses. In each case, better performance on these tasks was associated with higher levels of fractional anisotropy in task-relevant regions.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Esquizofrenia
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Encéfalo
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Transtornos Cognitivos
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Imagem de Difusão por Ressonância Magnética
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Testes Neuropsicológicos
Limite:
Adult
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article