Benign lymphangiomatous papules of the skin associated with ovarian fibroma.
J Am Acad Dermatol
; 56(2 Suppl): S41-4, 2007 Feb.
Article
em En
| MEDLINE
| ID: mdl-17097370
ABSTRACT
Benign lymphangiomatous papules of the skin are considered reactive lymphatic proliferations either caused by disruption of the lymphatic flow or tissue damage produced by operation or radiation therapy. We report a 72-year-old woman with umbilical papules and vesicle-like lesions that led to the diagnosis of a large ovarian fibroma. Histologic study revealed dilated lymphatic spaces manifesting an anastomosing and branched pattern in the papillary and reticular dermis dissecting collagen bundles. The vessels were lined by plump endothelial cells with foci of intravascular papillary endothelial cell hyperplasia. After the ovarian fibroma was removed by laparotomy, umbilical lesions almost disappeared, leaving small flesh-colored papules. A periumbilical dermatosis may herald certain intra-abdominal diseases including those of neoplastic derivation. A heightened awareness of this association may lead to an early diagnosis with a potential for improved patient outcome. Benign lymphangiomatous papules have not been previously described in association with an untreated tumor, without previous operation or radiotherapy. This case advocates for disruption of the lymphatic drainage as the probable pathogenetic mechanism.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Ovarianas
/
Neoplasias Cutâneas
/
Radiografia Abdominal
/
Tomografia Computadorizada por Raios X
/
Fibroma
/
Linfangioma
/
Neoplasias Primárias Múltiplas
Tipo de estudo:
Risk_factors_studies
/
Screening_studies
Limite:
Aged
/
Female
/
Humans
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article