Pharmacologic management of insomnia: past, present, and future.
Psychiatr Clin North Am
; 29(4): 871-93; abstract vii-viii, 2006 Dec.
Article
em En
| MEDLINE
| ID: mdl-17118273
ABSTRACT
Views on the etiology and morbidities associated with insomnia are evolving and affect clinicians' approach to the pharmacologic management of insomnia. Currently, benzodiazepine receptor agonists (BzRAs) and a single melatonin receptor agonist are recognized as safe and efficacious hypnotics. Variability in BzRAs, pharmacokinetics, and manipulation of dose provide clinicians with options that meet the needs of most patients. Other drugs (eg, sedating antidepressants) also are used commonly in clinical practice to treat insomnia, but evidence is lacking to support this most cases. Improvement in managing insomnia will result from systematic research with these drugs, with drugs in development, and with novel uses, such as co-therapy.
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Base de dados:
MEDLINE
Assunto principal:
Tratamento Farmacológico
/
Distúrbios do Início e da Manutenção do Sono
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article