Ovarian tissue cryostorage and grafting: an option to preserve fertility in pediatric patients with malignancies.
Pediatr Hematol Oncol
; 24(1): 29-44, 2007.
Article
em En
| MEDLINE
| ID: mdl-17130112
Fertility preservation in childhood cancer has become an important area of investigation due to increasing survival rates after cancer therapy. For these patients with an increased risk of infertility and premature ovarian failure, cryopreservation of ovarian tissue is a promising tool to preserve at least part of the reproductive potential. In recent years significant improvements have been achieved in this area, and 2 live births after autografting of frozen-thawed ovarian tissue have been reported. However, further research is needed to assess the clinical effectiveness of ovarian cryopreservation, to optimize the technique, and to limit the risk of reintroducing cancer cells in the patient with the graft.
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Base de dados:
MEDLINE
Assunto principal:
Ovário
/
Radioterapia
/
Criopreservação
/
Infertilidade Feminina
/
Antineoplásicos
Tipo de estudo:
Etiology_studies
Limite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article