[Neonatal diarrhoea in pigs: alpha- and beta2-toxin produced by Clostridium perfringens]. / Neonatale diarree bij biggen: alpha- en beta2-toxine producerende Clostridium perfringens.
Tijdschr Diergeneeskd
; 131(24): 910-3, 2006 Dec 15.
Article
em Nl
| MEDLINE
| ID: mdl-17278609
ABSTRACT
Since 2001 the Pig Health Unit of Utrecht University has been consulted by various pig farms regarding neonatal diarrhoea. When preventive measures against E. coli-induced diarrhoea had no or limited results, the diarrhoeic piglets were investigated further. The microbiological and pathological findings were indicative of infection with Clostridium perfringens. Toxin typing by polymerase chain reaction led to the detection of genes encoding a-toxin (cpa) and beta2-toxin (cpb2). Surprisingly, alpha- and beta2-toxin-producing C. perfringens was isolated from all tested herds with piglets with neonatal diarrhoea. From our observations, it is likely that many herds in the Netherlands are infected with beta2-toxin-producing C. perfringens strains. As present vaccines lack beta2-toxoid and thus do not provide piglets with protection against beta2-induced diarrhoea.
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Base de dados:
MEDLINE
Assunto principal:
Doenças dos Suínos
/
Toxinas Bacterianas
/
Infecções por Clostridium
/
Clostridium perfringens
/
Diarreia
Limite:
Animals
País como assunto:
Europa
Idioma:
Nl
Ano de publicação:
2006
Tipo de documento:
Article