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Discordant response of glutathione and thioredoxin systems in human hypertension?
Mansego, Maria L; Blesa, Sebastian; Gonzalez-Albert, Veronica; Tormos, Maria C; Saez, Guillermo; Redon, Josep; Chaves, Felipe J.
Afiliação
  • Mansego ML; Laboratorio de Estudios Genéticos. Fundación para la Investigación del Hospital Clínico, Valencia, Spain.
Antioxid Redox Signal ; 9(4): 507-14, 2007 Apr.
Article em En | MEDLINE | ID: mdl-17280491
Hypertension is frequently associated with oxidative stress caused by high production of reactive oxygen species and compromised antioxidant defenses. Humans with essential hypertension, with or without treatment, and controls were examined (35 hypertensive and 30 normotensive). We noted a discordant response of the glutathione and thioredoxin systems in essential hypertension and to antihypertensive treatment. Further studies examining the significance of these thiols in hypertension outcomes are warranted.
Assuntos
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Base de dados: MEDLINE Assunto principal: Tiorredoxinas / Glutationa / Hipertensão Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2007 Tipo de documento: Article
Buscar no Google
Base de dados: MEDLINE Assunto principal: Tiorredoxinas / Glutationa / Hipertensão Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2007 Tipo de documento: Article