[Risk of HIV-1 or 2 infection associated with transfusion in Benin]. / Risque infectieux VIH 1/2 transfusionnel au Bénin.
Bull Soc Pathol Exot
; 97(4): 261-4, 2004 Nov.
Article
em Fr
| MEDLINE
| ID: mdl-17304747
ABSTRACT
OBJECTIVE:
To evaluate the residual risk of transmission of HIV 1/2 infection through transfusion of seronegative blood.METHODS:
This study was carried out between January and July 2000. It was based on eight hundred and twenty-one (821) blood donors screened negative for HIV antibodies by ELISA using Vironostika Uni-form II plus 0 (Organon Teknika). 675 (82.2%) were men and 146 (17.8%) women all aged between 18 and 56 years with a mean age of 25.5 +/- 7.8 years. Serum aliquots of these seronegative blood donor were frozen and further tested with two tests Enzymun-Test HIV Combi (Roche Immunodiagnostics) and Murex HIV Antigen Mab (Murex).RESULTS:
Twenty six out of 821 (3.2%) seronegative specimens were repeatedly reactive for Enzymun-test. All were tested negative once again for anti-HIV antibodies by ELISA using Vironostika Uni-form II/plus 0. Out of these 26, only one was repeatedly reactive for Murex. For further analysis of the 25 donors tested negative for Murex, only 9 came back for another donation five months later. All of them were tested negative for anti-HIV antibodies by ELISA (Vironostika).CONCLUSION:
Our study shows the existence of residual risk of transmission of HIV1/2 infection associated with transfusion of seronegative blood donors. This risk was higher in our countries compared with industrialised nations. Therefore implementing strategies should be a priority to avoid the residual risk and improve blood transfusion safety.
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Base de dados:
MEDLINE
Assunto principal:
Doadores de Sangue
/
Sorodiagnóstico da AIDS
/
Infecções por HIV
/
HIV-1
/
HIV-2
/
Reação Transfusional
Tipo de estudo:
Clinical_trials
/
Diagnostic_studies
/
Etiology_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Middle aged
País como assunto:
Africa
Idioma:
Fr
Ano de publicação:
2004
Tipo de documento:
Article