Acute hepatitis with severe cholestasis and prolonged clinical course due to hepatitis A virus Ia and Ib coinfection.
Clin Infect Dis
; 44(9): e73-7, 2007 May 01.
Article
em En
| MEDLINE
| ID: mdl-17407028
ABSTRACT
BACKGROUND:
Acute viral hepatitis due to hepatitis A virus is a self-limited illness that infrequently has a severe clinical course.METHODS:
We analyzed the virological characteristics of acute hepatitis A in a patient with a severe clinical presentation (peak total and conjugated bilirubin levels, 65.5 mg/dL and 40.1 mg/dL, respectively) and a course of disease that lasted 7 months.RESULTS:
Hepatitis A virus sequencing revealed coinfection with 2 subgenotypes of hepatitis A virus (Ia and Ib) as etiological factors of the illness.CONCLUSIONS:
Hepatitis A virus Ia and Ib coinfection may have accounted for the prolonged and severe course of illness.
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Base de dados:
MEDLINE
Assunto principal:
Colestase
/
Vírus da Hepatite A
/
Hepatite A
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article