The standardized surgical approach improves outcome of gallbladder cancer.
World J Surg Oncol
; 5: 55, 2007 May 21.
Article
em En
| MEDLINE
| ID: mdl-17517122
ABSTRACT
BACKGROUND:
The objective of this study was to examine the extent of surgical procedures, pathological findings, complications and outcome of patients treated in the last 12 years for gallbladder cancer.METHODS:
The impact of a standardized more aggressive approach compared with historical controls of our center with an individual approach was examined. Of 53 patients, 21 underwent resection for cure and 32 for palliation.RESULTS:
Overall hospital mortality was 9% and procedure related mortality was 4%. The standardized approach in UICC stage IIa, IIb and III led to a significantly improved outcome compared to patients with an individual approach (Median survival 14 vs. 7 months, mean+/-SEM 26+/-7 vs. 17+/-5 months, p = 0.014). The main differences between the standardized and the individual approach were anatomical vs. atypical liver resection, performance of systematic lymph dissection of the hepaticoduodenal ligament and the resection of the common bile duct.CONCLUSION:
Anatomical liver resection, proof for bile duct infiltration and, in case of tumor invasion, radical resection and lymph dissection of the hepaticoduodenal ligament are essential to improve outcome of locally advanced gallbladder cancer.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Colecistectomia
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Neoplasias da Vesícula Biliar
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Hepatectomia
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Linfonodos
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Invasividade Neoplásica
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Recidiva Local de Neoplasia
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
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Observational_studies
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Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article