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Survival analysis after surgical treatment of gastric cancer: review of 121 cases.
Nazli, Okay; Derici, Hayrullah; Tansug, Tugrul; Yaman, Ismail; Bozdag, Ali Dogan; Isgüder, Ali Serdar; Bölükbasi, Hakan.
Afiliação
  • Nazli O; Third Surgical Clinic, Atatürk Training and Research Hospital, Izmir, Turkey. okaynazli@hotmail.com
Hepatogastroenterology ; 54(74): 625-9, 2007 Mar.
Article em En | MEDLINE | ID: mdl-17523337
BACKGROUND/AIMS: This study was performed to evaluate major morbidity, early mortality and to analyze survival in our patients that underwent surgical treatment for gastric cancer. METHODOLOGY: Records of 121 patients with gastric adenocarcinoma that underwent surgery between 1997 and 2004 were reviewed retrospectively. Age, gender, tumor site, presence of local invasion, depth of tumor invasion, lymph node metastases, stage of the disease, distant metastases, histological differentiation, type of surgery, and blood transfusions were evaluated in relation to survival. Survival curves were estimated using the Kaplan-Meier method and the differences in survival were compared by the log-rank test. RESULTS: Forty-two cases (34.7%) underwent total gastrectomy, 34 (28.1%) had subtotal gastrectomy, and 45 (37.2%) received palliative surgery. The majority of the patients (61.2%) had stage IV gastric cancer. Total morbidity and mortality were 26.4% and 17.3%, respectively. The factors that influence survival were type of surgery, adjacent organ invasion, existence of metastases, lymph node status, blood transfusions, and stage of the disease in this study. Among the significant prognostic factors in the univariate analysis, only one factor, R0 resection proved to be independently significant in the multivariate analysis. CONCLUSIONS: R0 resection was found to have a significant favorable effect on survival in our study.
Assuntos
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Base de dados: MEDLINE Assunto principal: Complicações Pós-Operatórias / Neoplasias Gástricas / Adenocarcinoma Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País como assunto: Asia Idioma: En Ano de publicação: 2007 Tipo de documento: Article
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Base de dados: MEDLINE Assunto principal: Complicações Pós-Operatórias / Neoplasias Gástricas / Adenocarcinoma Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País como assunto: Asia Idioma: En Ano de publicação: 2007 Tipo de documento: Article