Finasteride and doxazosin alone or in combination for the treatment of benign prostatic hyperplasia.
Expert Opin Pharmacother
; 8(9): 1337-44, 2007 Jun.
Article
em En
| MEDLINE
| ID: mdl-17563267
ABSTRACT
Benign prostatic hyperplasia is an increasingly prevalent condition affecting > 50% of men > 65 years of age. Although it is a condition that is unlikely to be life threatening, it can significantly affect quality of life with distressing lower urinary tract symptoms. Increasingly, medical therapy is being used as first-line treatment for men with moderate-to-severe lower urinary tract symptoms. Two main pharmacological classes of drugs are used 5alpha-reductase inhibitors and alpha-1 selective blockers. Both these classes of drugs have shown good tolerability and clinical efficacy. This article examines the potential benefit of the use of combination therapy. In particular, what is the evidence for using doxazosin and finasteride therapy together?
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Base de dados:
MEDLINE
Assunto principal:
Hiperplasia Prostática
/
Doxazossina
/
Finasterida
/
Antagonistas Adrenérgicos alfa
/
Inibidores Enzimáticos
Limite:
Aged
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article