Risk factors for pathologic gambling and other compulsions among Parkinson's disease patients taking dopamine agonists.
J Clin Neurosci
; 14(12): 1178-81, 2007 Dec.
Article
em En
| MEDLINE
| ID: mdl-17720504
ABSTRACT
Three hundred patients with Parkinson's disease taking dopamine agonists were surveyed for the presence of compulsions. Fifty-eight reported active compulsions which had developed after initiation of dopamine agonists. These included 25 with sexual compulsions and 28 with self-described compulsive gambling, of whom 17 met criteria for pathologic gambling. Males were over-represented. Patients with any compulsion and those with pathologic gambling were about 6 years younger than those without compulsions. These behavioral problems were not associated with an individual dopamine agonist, nor dose or duration, nor concomitant levodopa. Follow-up of the pathologic gamblers 1 year after intervention, which was cessation of the dopamine agonist in most cases, found ongoing but controlled gambling in five and complete cessation within 4 months in the remainder.
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Base de dados:
MEDLINE
Assunto principal:
Doença de Parkinson
/
Comportamento Compulsivo
/
Agonistas de Dopamina
/
Jogo de Azar
/
Antiparkinsonianos
Tipo de estudo:
Etiology_studies
/
Qualitative_research
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article