Putting the glue in glia: Necls mediate Schwann cell axon adhesion.
J Cell Biol
; 178(5): 721-3, 2007 Aug 27.
Article
em En
| MEDLINE
| ID: mdl-17724116
ABSTRACT
Interactions between Schwann cells and axons are critical for the development and function of myelinated axons. Two recent studies (see Maurel et al. on p. 861 of this issue; Spiegel et al., 2007) report that the nectin-like (Necl) proteins Necl-1 and -4 are internodal adhesion molecules that are critical for myelination. These studies suggest that Necl proteins mediate a specific interaction between Schwann cells and axons that allows proper communication of the signals that trigger myelination.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Células de Schwann
/
Axônios
/
Moléculas de Adesão Celular Neuronais
/
Adesão Celular
Limite:
Animals
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article