[Clinical and pathologic features of melanocytic lesion of the central nervous system].
Zhong Nan Da Xue Xue Bao Yi Xue Ban
; 32(4): 713-7, 2007 Aug.
Article
em Zh
| MEDLINE
| ID: mdl-17767073
ABSTRACT
OBJECTIVE:
To investigate the clinical and pathologic features of melanocytic lesion of the central nervous system.METHODS:
We analyzed the clinical features, neuroimages, and operational and neuropathological findings of 2 patients of neurocutaneous melanosis and 4 patients of primary leptomeningeal melanoma.RESULTS:
All the 6 patients had the common clinical features of intracranial hypertension and epilepsy. Brain CT and MRI showed abnormal signals. More melanin pigment nevi were found on the skin of the 2 patients subjected to neurocutaneous melanosis. The other 4 patients subjected to primary leptomeningeal melanoma had no melanin pigment nevus on the skin, but the brain section displayed positive meningeal melanoma.CONCLUSION:
Intracranial hypertension and epilepsy are the main clinical manifestations of melanocytic lesion of the central nervous system, and cutaneous lesion and radiological findings are very important for the diagnosis.
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Base de dados:
MEDLINE
Assunto principal:
Síndromes Neurocutâneas
/
Melanose
/
Doenças do Sistema Nervoso
Limite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Ano de publicação:
2007
Tipo de documento:
Article