Development of new sensitizations in asthmatic children monosensitized to house dust mite by specific immunotherapy.
Asian Pac J Allergy Immunol
; 25(1): 7-11, 2007 Mar.
Article
em En
| MEDLINE
| ID: mdl-17891916
ABSTRACT
It has been hypothesized that specific immunotherapy (SIT) significantly decreases the development of new allergen sensitizations in mono-sensitized patients. In this study, we evaluated the effect of SIT on the development of new allergen sensitizations in 129 asthmatic children mono-sensitized to house dust mite. SIT was accepted by only 70 of them (SIT group). The remaining 59 children were treated only with medication (control group). At the end of the study we found that 33% of all patients developed new sensitizations. Surprisingly, the prevalence of new sensitizations was significantly higher in the SIT group (45.5%) than in the control group (18.1 %). Ash tree (Fraxinus excelsior), Olive and Meadow fescue (Festuca elatior) were the most common allergens responsible for the new sensitizations. We conclude that SIT did not prevent the onset of new sensitizations in asthmatic children mono-sensitized to house dust mite.
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Base de dados:
MEDLINE
Assunto principal:
Asma
/
Dessensibilização Imunológica
/
Pyroglyphidae
/
Hipersensibilidade
Tipo de estudo:
Risk_factors_studies
Limite:
Animals
/
Child
/
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article