Synthesis and antifungal bioactivities of 3-alkylquinazolin- 4-one derivatives.
Molecules
; 11(6): 383-92, 2006 Jun 12.
Article
em En
| MEDLINE
| ID: mdl-17962771
ABSTRACT
A simple, efficient, and general method has been developed for the synthesis of various 3-alkylquinazolin-4-one derivatives from quinazolin-4-one treated with alkyl bromides under phase transfer catalysis condition. The structures of the compounds were characterized by elemental analysis, IR, (1)H-NMR and (13)C-NMR spectra. Title compound 6-bromo-3-propylquinazolin-4-one (3h) was found to possess good antifungal activity.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Quinazolinonas
/
Antifúngicos
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article