Skeletal muscle satellite cells and adult myogenesis.
Curr Opin Cell Biol
; 19(6): 628-33, 2007 Dec.
Article
em En
| MEDLINE
| ID: mdl-17996437
ABSTRACT
Research focusing on the canonical adult myogenic progenitor, the skeletal muscle satellite cell, is still an ever-growing field 46 years from their initial description. Recent publications revealed numerous new aspects of satellite cell biology, starting from their developmental life to their role as the principal self-renewing myogenic stem cell in adult skeletal muscle and finally their loss during aging. The myogenic potential of satellite cells is under the molecular control of specific paired-box and bHLH transcription factors whose tightly orchestrated balance accounts for an effective skeletal muscle regeneration. New reports also demonstrate satellite cells relationships with blood vessels and the high myogenic potential of stem cell subsets related to both lineages.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Desenvolvimento Muscular
/
Células Satélites de Músculo Esquelético
Limite:
Adult
/
Humans
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article