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PKR and PKR-like endoplasmic reticulum kinase induce the proteasome-dependent degradation of cyclin D1 via a mechanism requiring eukaryotic initiation factor 2alpha phosphorylation.
Raven, Jennifer F; Baltzis, Dionissios; Wang, Shuo; Mounir, Zineb; Papadakis, Andreas I; Gao, Hong Qing; Koromilas, Antonis E.
Afiliação
  • Raven JF; Department of Oncology, Faculty of Medicine, McGill University, Montreal, Quebec H2W 1S6, Canada; Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Quebec H3T 1E2, Canada.
  • Baltzis D; Department of Oncology, Faculty of Medicine, McGill University, Montreal, Quebec H2W 1S6, Canada; Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Quebec H3T 1E2, Canada.
  • Wang S; Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Quebec H3T 1E2, Canada.
  • Mounir Z; Department of Oncology, Faculty of Medicine, McGill University, Montreal, Quebec H2W 1S6, Canada; Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Quebec H3T 1E2, Canada.
  • Papadakis AI; Department of Oncology, Faculty of Medicine, McGill University, Montreal, Quebec H2W 1S6, Canada; Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Quebec H3T 1E2, Canada.
  • Gao HQ; Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Quebec H3T 1E2, Canada.
  • Koromilas AE; Department of Oncology, Faculty of Medicine, McGill University, Montreal, Quebec H2W 1S6, Canada; Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Quebec H3T 1E2, Canada. Electronic address: antonis.koromilas@mcgill.ca.
J Biol Chem ; 283(6): 3097-3108, 2008 Feb 08.
Article em En | MEDLINE | ID: mdl-18063576
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator de Iniciação 2 em Eucariotos / Regulação da Expressão Gênica / EIF-2 Quinase / Ciclina D1 Limite: Humans Idioma: En Ano de publicação: 2008 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator de Iniciação 2 em Eucariotos / Regulação da Expressão Gênica / EIF-2 Quinase / Ciclina D1 Limite: Humans Idioma: En Ano de publicação: 2008 Tipo de documento: Article