Decimative subspace-based parameter estimation methods of magnetic resonance spectroscopy based on prior knowledge.

ABSTRACT

The method Hankel Total Least Squares (HTLS)-PK, which successfully incorporates prior knowledge of known signal poles into the method HTLS, has been proven to greatly improve the performance for parameter estimation of overlapping peaks of magnetic resonance spectroscopy (MRS) signal. In addition, decimation is also proposed as a way to increase the performance of subspace-based parameter estimation methods in the case of oversampling. Taking advantage of decimation in combination with prior knowledge to estimate the MRS signal parameters, two novel subspace-based parameter estimation methods, HTLSDSumPK and HTLSDStackPK, are presented in this paper. The experimental results and relevant analysis show that the methods HTLSDSumPK, HTLSDStackPK and HTLS-PK are slightly better than the method HTLS at low noise levels; however, the three prior-knowledge-incorporating methods, especially the method HTLSDSumPK, have much better performance than the method HTLS at high noise levels in the terms of robustness, estimated accuracy and computational complexity. Even if some inaccuracy of prior knowledge is considered, the method HTLSDSumPK also shows some advantages.