Lack of alloantigen-specific cytotoxic T cell activity in the TCR-gamma delta T cell subpopulation of alloantigen-immune chickens.
Curr Top Microbiol Immunol
; 173: 93-7, 1991.
Article
em En
| MEDLINE
| ID: mdl-1833164
ABSTRACT
We examined the in vivo generation of alloantigen-specific cytotoxic T lymphocytes in chicken TCR-alpha beta and TCR-gamma delta T cells. The TCR-alpha beta and TCR-gamma delta subpopulations were separated from spleen of alloantigen-immune chickens using a negative selection method. The separated cells were examined for alloantigen-specific CTL activity in a 51Cr release assay. While negatively selected TCR-alpha beta cells exerted alloantigen-specific CTL activity, no cytotoxic activity could be detected with TCR-gamma delta cells.
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Base de dados:
MEDLINE
Assunto principal:
Linfócitos T Citotóxicos
/
Receptores de Antígenos de Linfócitos T gama-delta
Limite:
Animals
Idioma:
En
Ano de publicação:
1991
Tipo de documento:
Article