Three-dimensional motion and perfusion quantification in gated single-photon emission computed tomograms.
J Nucl Med
; 32(12): 2311-7, 1991 Dec.
Article
em En
| MEDLINE
| ID: mdl-1836022
ABSTRACT
Methods for quantification and display of left ventricular (LV) functional parameters from gated single-photon emission computed tomographs are described. Using previously documented surface detection methods, we developed techniques for calculating global variables, such as volumes and areas, as well as local variables such as segmental motion and local perfusion from gated tomographic radionuclide ventriculograms (TRVG) and gated perfusion tomograms (sestamibi). We have developed three-dimensional displays to allow realistic visualizations of the results. The motion results have been validated using correlative magnetic resonance imaging (MRI) studies; motion calculated from user-traced MR images of the heart was compared to motion calculated from automatically detected surfaces in TRVG and sestamibi. The average motion error was calculated to be 0.67 mm in TRVG and -0.21 mm in sestamibi. Errors were largest in basal LV regions; we explain this phenomenon using simulations. Finally, we present additional examples of the analysis using studies obtained from normal volunteers and from subjects whose coronary artery anatomies were known.
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Base de dados:
MEDLINE
Assunto principal:
Processamento de Imagem Assistida por Computador
/
Imagem do Acúmulo Cardíaco de Comporta
/
Tomografia Computadorizada de Emissão de Fóton Único
Limite:
Humans
Idioma:
En
Ano de publicação:
1991
Tipo de documento:
Article