Synthetic studies on maitotoxin. 3. Stereoselective synthesis of the BCDE-ring system.
Org Lett
; 10(9): 1683-5, 2008 May 01.
Article
em En
| MEDLINE
| ID: mdl-18393509
ABSTRACT
The stereoselective synthesis of the BCDE-ring system of maitotoxin has been accomplished through a two-directional strategy for the construction of polycyclic ether. The key reactions involve SmI 2-induced double cyclization of a beta-alkoxyacrylate and a double dihydroxylation for construction of the B- and E-rings.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Compostos Policíclicos
/
Oxocinas
/
Éteres
/
Toxinas Marinhas
Limite:
Animals
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article