Somatosensory-evoked fields on magnetoencephalography for epilepsy infants younger than 4 years with total intravenous anesthesia.
Clin Neurophysiol
; 119(6): 1328-34, 2008 Jun.
Article
em En
| MEDLINE
| ID: mdl-18406202
ABSTRACT
OBJECTIVE:
Patients must remain immobile for magnetoencephalography (MEG) and MRI recordings to allow precise localization of brain function for pre-surgical functional mapping. In young children with epilepsy, this is accomplished with recordings during sleep or with anesthesia. This paper demonstrates that MEG can detect, characterize and localize somatosensory-evoked fields (SEF) in infants younger than 4 years of age with or without total intravenous anesthesia (TIVA).METHODS:
We investigated the latency, amplitude, residual error (RE) and location of the N20m of the SEF in 26 infants (mean age=2.6 years). Seventeen patients underwent TIVA and 9 patients were tested while asleep, without TIVA.RESULTS:
MEG detected 44 reliable SEFs (77%) in 52 median nerve stimulations. We found 27 reliable SEFs (79%) with TIVA and 13 reliable SEFs (72%) without TIVA. TIVA effects included longer latencies (p<0.001) and lower RE (p<0.05) compared to those without TIVA. Older patients and larger head circumferences also showed significantly shorter latencies (p<0.01).CONCLUSIONS:
TIVA resulted in reliable SEFs with lower RE and longer latencies.SIGNIFICANCE:
MEG can detect reliable SEFs in infants younger than 4 years old. When infants require TIVA for MEG and MRI acquisition, SEFs can still be reliably observed.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Mapeamento Encefálico
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Epilepsia
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Potenciais Somatossensoriais Evocados
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Anestesia
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Anestesia Intravenosa
Limite:
Child, preschool
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Female
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Humans
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Infant
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Male
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article