Seroprevalence of human parvovirus B19 in a suburban population in São Paulo, Brazil.
Rev Saude Publica
; 42(3): 443-9, 2008 Jun.
Article
em En
| MEDLINE
| ID: mdl-18425294
ABSTRACT
OBJECTIVE:
To analyze the prevalence of IgG antibodies to human parvovirus B19.METHODS:
Cross-sectional study in a suburban community in São Paulo, Southeastern Brazil, between November 1990 and January 1991. Randomly selected (N=435) representative samples of sera were collected from healthy children older than 15 days old and adults up to 40 years old. IgG antibodies were detected using ELISA.RESULTS:
High prevalence of IgG antibodies to B19 parvovirus was found in 87% of newborns. The prevalence of maternally derived IgG antibodies exponentially plunged up to the 19th month of age. Low prevalence of antibodies was found in the first 4 years of life, increasing up to 72% in those aged 31-40 years. It was estimated that the average age of first infection in this population is 21 +/- 7 years old and the optimal age for vaccination with a hypothetical vaccine would be 1 year of age.CONCLUSIONS:
Parvovirus B19 IgG antibody prevalence was high in newborns and those aged 31-40 years. The analysis by age groups showed a pattern similar to that found in previous studies, i.e., low prevalence of infection in children that increases with age.
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Base de dados:
MEDLINE
Assunto principal:
Imunoglobulina G
/
Parvovirus B19 Humano
/
Infecções por Parvoviridae
/
Anticorpos Antivirais
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
País como assunto:
America do sul
/
Brasil
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article