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[Patogenetic therapy of patients with diabetes mellitus type 2 and cerebral vascular insufficiency].
Article em Ru | MEDLINE | ID: mdl-18427536
Effectiveness of halidor preparation was assessed in a randomized open 8-weeks study in 44 patients with diabetes mellitus type 2 and chronic cerebral blood circulation disorders. A control group included 15 patients with the same pathologies who did not receive halidor. Administration of halidor in doses 100 mg 3 times daily led to the improvement of clinical state in 32 (72,7%) patients that was confirmed by statistically better performance (p<0,05) on the neuropsychological tests: MMSE by 14,7%, clock-drawing test by 16,8%, the Schult test by 23,5%. The blood flow in middle and posterior cerebral arteries was increased by 21 and 23%, respectively (p<0,05), and the vascular tonus was reduced. The possibility of halidor administration to patients with diabetes mellitus with concomitant chronic cerebral blood circulation disorders is discussed.
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Base de dados: MEDLINE Assunto principal: Vasodilatadores / Benciclano / Bloqueadores dos Canais de Cálcio / Transtornos Cerebrovasculares / Diabetes Mellitus Tipo 2 / Angiopatias Diabéticas Tipo de estudo: Clinical_trials / Etiology_studies / Risk_factors_studies Limite: Humans / Male / Middle aged Idioma: Ru Ano de publicação: 2008 Tipo de documento: Article
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Base de dados: MEDLINE Assunto principal: Vasodilatadores / Benciclano / Bloqueadores dos Canais de Cálcio / Transtornos Cerebrovasculares / Diabetes Mellitus Tipo 2 / Angiopatias Diabéticas Tipo de estudo: Clinical_trials / Etiology_studies / Risk_factors_studies Limite: Humans / Male / Middle aged Idioma: Ru Ano de publicação: 2008 Tipo de documento: Article