Bacterial adherence to SiO2-based multifunctional bioceramics.
J Biomed Mater Res A
; 89(1): 215-23, 2009 Apr.
Article
em En
| MEDLINE
| ID: mdl-18431760
ABSTRACT
The bacterial adherence onto different multifunctional silica-based bioceramics has been evaluated. Staphylococcus aureus and Staphylococcus epidermidis were chosen, as they cause the majority of the implant-related infections in this field. Two SiO2 mesoporous materials (MCM-41, SBA-15), an ordered SiO2-CaO-P2O5 mesoporous glass (OMG), and a biphasic magnetic bioceramic (BMB), were incubated with S. aureus and S. epidermidis for 90 min, and subsequently sonicated to quantify the number of adhered bacteria on each material. It was found that S. aureus and S. epidermidis (10(8) CFU/mL) adhered significantly less to BMB samples when compared to MCM-41, SBA-15, or OMG. However, when the material pores accessible for bacteria in each material were taken into account, the lowest bacterial adherence was found in MCM-41, and the highest in SBA-15. The results show that bacterial adherence is higher on mesoporous bioceramics, although this higher microbial attachment is mainly due to the intergranular porosity and grain size morphology rather than to the mesoporous structure.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Staphylococcus aureus
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Staphylococcus epidermidis
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Materiais Biocompatíveis
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Aderência Bacteriana
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Cerâmica
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Dióxido de Silício
Limite:
Humans
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article