Puma: mauling the intestinal crypt.
Cell Stem Cell
; 2(6): 517-8, 2008 Jun 05.
Article
em En
| MEDLINE
| ID: mdl-18522842
ABSTRACT
Cancer therapies utilizing chemotherapy or radiotherapy are constrained by risk of intestinal stem cell death. In this issue of Cell Stem Cell, Qiu et al. report that Puma deletion prevents intestinal degeneration following DNA damage, thus offering a target protein for the design of enhanced cancer treatments.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Lesões Experimentais por Radiação
/
Proteínas Supressoras de Tumor
/
Trato Gastrointestinal
/
Proteínas Reguladoras de Apoptose
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Células-Tronco Adultas
Limite:
Animals
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article