Vinyl quinones as Diels-Alder dienes: concise synthesis of (-)-halenaquinone.
J Am Chem Soc
; 130(27): 8604-5, 2008 Jul 09.
Article
em En
| MEDLINE
| ID: mdl-18549215
ABSTRACT
A concise asymmetric synthesis of (-)-halenaquinone is described. The synthesis features a diastereoselective Heck cyclization to set a quaternary center as well as a novel intramolecular inverse-electron-demand Diels-Alder reaction involving a vinyl quinone. The synthesis is highly convergent and features a minimal amount of protecting group manipulations.
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1
Base de dados:
MEDLINE
Assunto principal:
Quinonas
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article