[Empirical antibiotic therapy for febrile neutropenia]. / Antibiothérapie empirique lors de neutropénie fébrile.
Rev Med Suisse
; 4(152): 914, 916-9, 2008 Apr 09.
Article
em Fr
| MEDLINE
| ID: mdl-18578432
ABSTRACT
Immediate broad-spectrum empirical antibacterial therapy is the key of management in febrile neutropenic patients. These patients can be stratified according to the risk of complications with the clinical MASCC score. Patients at low risk of complications can be efficaciously treated with oral antibiotics (e.g. fluoroquinolone and beta-lactam), provided that compliance and drug absorption are adequate. Early discharge is possible if clinical, logistic, and social criteria are fulfilled. Intravenous antibiotic therapy with broad-spectrum beta-lactam antibiotics in the hospital remains the standard in high-risk patients. The empirical addition of an aminoglycoside and/or a glycopeptide is recommended if the local incidence of infections due to beta-lactam resistant pathogens is high or in critically ill septic patients.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Febre
/
Antibacterianos
/
Neutropenia
Limite:
Humans
Idioma:
Fr
Ano de publicação:
2008
Tipo de documento:
Article