Phase-modulation laser interference microscopy: an advance in cell imaging and dynamics study.
J Biomed Opt
; 13(3): 034004, 2008.
Article
em En
| MEDLINE
| ID: mdl-18601549
ABSTRACT
We describe how phase-modulation laser interference microscopy and wavelet analysis can be applied to noninvasive nonstained visualization and study of the structural and dynamical properties of living cells. We show how phase images of erythrocytes can reveal the difference between various erythrocyte forms and stages of hemolysis and how phase images of neurons reveal their complex intracellular structure. Temporal variations of the refractive index are analyzed to detect cellular rhythmic activity on different time scales as well as to uncover interactions between the cellular processes.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Aumento da Imagem
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Microscopia de Contraste de Fase
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Microscopia Confocal
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Tomografia de Coerência Óptica
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Eritrócitos
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Interferometria
Limite:
Humans
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article