Atrophoderma of Pasini and Pierini: a clinical and histopathological study.
J Cutan Pathol
; 35(12): 1108-14, 2008 Dec.
Article
em En
| MEDLINE
| ID: mdl-18616761
ABSTRACT
BACKGROUND:
Idiopathic atrophoderma of Pasini and Pierini (IAPP) usually manifests as one or multiple depressed and hyperpigmented patches, with a predilection to the trunk. No diagnostic changes are usually seen on histology. Elastic stains often reveal no abnormalities.OBJECTIVE:
To review our cases of IAPP, describe their clinical and histological findings and compare them with the literature.METHODS:
Retrospective review of IAPP cases who presented to our institution between 1994 and 2006.RESULTS:
From a total of 16 patients, only 19% displayed hyperpigmented lesions, while 81% had either hypopigmented (9/16) or skin-colored (4/16) lesions. The sites predominantly affected were the lower extremities (62.5%), followed by the upper extremities and trunk. Only in one patient was IAPP co-existent with morphea. Histology revealed no diagnostic abnormalities; however, elastic stains showed a spectrum of changes ranging from normal to severe diminution and fragmentation of elastic fiber network.CONCLUSIONS:
Our study shows several new aspects of IAPP. Clinically, the lesions were most commonly hypopigmented and involved predominantly the extremities. Histologically, IAPP exhibited a spectrum of alterations in elastic fibers. The most prevalent form of IAPP in our country seems to be unassociated with morphea.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Dermatopatias
Tipo de estudo:
Observational_studies
Limite:
Adolescent
/
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article