Is there any clinical parameter able to predict prostate cancer after initial diagnosis of atypical small acinar proliferation?
Urol Int
; 81(1): 29-35, 2008.
Article
em En
| MEDLINE
| ID: mdl-18645268
ABSTRACT
INTRODUCTION:
Tissue samples from prostate biopsy may contain atypical small acinar proliferation (ASAP) present guidelines recommend a repeat biopsy policy. This study attempted to identify clinical patterns that help predict cancer detection at second biopsy. MATERIALS ANDMETHODS:
From 1999 to 2005, 1,274 patients underwent a prostate biopsy in 5.9% ASAP was found, and patients underwent a second biopsy. Uni- and multivariate analysis compared the clinical patterns of cancer patients with the no cancer group at second biopsy.RESULTS:
Univariate analysis showed significant differences in PSA ratio density, prostate volume, final PSA values and Delta PSA; at multivariate logistic regression analysis, only PSA ratio (OR = 0.743, 95% CI 0.620-0.891) and prostate volume (OR = 0.960, 95% CI 0.924-0.998) were predictive of malignancy.CONCLUSIONS:
In our experience, PSA ratio and prostate volume seem to be independent predictors of prostate cancer at re-biopsy.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Próstata
/
Proliferação de Células
Tipo de estudo:
Diagnostic_studies
/
Guideline
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Aged80
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article