Pyrrolizidine alkaloids from Echium glomeratum (Boraginaceae).
Phytochemistry
; 69(12): 2341-6, 2008 Sep.
Article
em En
| MEDLINE
| ID: mdl-18691727
ABSTRACT
The methanolic extract of the whole plant of Echium glomeratum Poir. (Boraginaceae) has afforded five pyrrolizidine alkaloids, three that were (7S, 8R)-petranine (1), (7S, 8S)-petranine (2), and (7R, 8R)-petranine (3a) or (7R, 8S)-petranine (3b), comprising a tricyclic pyrrolizidine alkaloids subclass; and two that were known but to the species 7-angeloylretronecine (4) and 9-angeloylretronecine (5). All compounds were tested against a human tumor panel for cytotoxicity; no activity was observed (EC50 values>20microg/ml).
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Alcaloides de Pirrolizidina
/
Echium
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article