A decade of genome-wide gene expression profiling in acute myeloid leukemia: flashback and prospects.
Blood
; 113(2): 291-8, 2009 Jan 08.
Article
em En
| MEDLINE
| ID: mdl-18703705
ABSTRACT
The past decade has shown a marked increase in the use of high-throughput assays in clinical research into human cancer, including acute myeloid leukemia (AML). In particular, genome-wide gene expression profiling (GEP) using DNA microarrays has been extensively used for improved understanding of the diagnosis, prognosis, and pathobiology of this heterogeneous disease. This review discusses the progress that has been made, places the technologic limitations in perspective, and highlights promising future avenues.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Leucemia Mieloide Aguda
/
Regulação Leucêmica da Expressão Gênica
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Genoma Humano
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Perfilação da Expressão Gênica
Limite:
Humans
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article