African trypanosomes contain 5-methylcytosine in nuclear DNA.
Eukaryot Cell
; 7(11): 2012-6, 2008 Nov.
Article
em En
| MEDLINE
| ID: mdl-18791035
ABSTRACT
It is currently unclear if there are modified DNA bases in Trypanosoma brucei other than J-base. We identify herein a cytosine-5 DNA methyltransferase gene and report the presence and location of 5-methylcytosine in genomic DNA. Our data demonstrate that African trypanosomes contain a functional cytosine DNA methylation pathway.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Trypanosoma brucei brucei
/
DNA de Protozoário
/
Metilação de DNA
/
5-Metilcitosina
Limite:
Animals
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article