Pseudohypoparathyroidism Ia with Evans syndrome.
J Pediatr Hematol Oncol
; 30(8): 628-30, 2008 Aug.
Article
em En
| MEDLINE
| ID: mdl-18799944
ABSTRACT
Pseudohypoparathyroidism Ia (Albright hereditary osteodystrophy or Albright syndrome) is a rare disease, caused by the resistance to the action of the parathyroid hormone in target tissues, such as the bone, kidney, and intestine, with consequent hypocalcemia and hyperphosphatemia and increased levels of parathyroid hormone. The phenotype of Albright syndrome includes 5 common features brachydactyly, obesity, short stature, a round face, and mental retardation. We report on a child with a classic form of pseudohypoparathyroidism and associated Albright syndrome who developed Evans syndrome (ie, the cooccurrence of severe autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura). To our knowledge, no cases of Evans syndrome have been observed associated with pseudohypoparathyroidism 1a.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pseudo-Hipoparatireoidismo
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Púrpura Trombocitopênica Idiopática
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Anemia Hemolítica Autoimune
Limite:
Child, preschool
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article