Sequence structure of hidden 10.4-base repeat in the nucleosomes of C. elegans.
J Biomol Struct Dyn
; 26(3): 273-82, 2008 Dec.
Article
em En
| MEDLINE
| ID: mdl-18808193
ABSTRACT
By measuring prevailing distances between YY, YR, RR, and RY dinucleotides in the large database of the nucleosome DNA fragments from C. elegans, the consensus sequence structure of the nucleosome DNA repeat of C. elegans was reconstructed (YYYYYRRRRR)n. An actual period was estimated to be 10.4 bases. The pattern is fully consistent with the nucleosome DNA patterns of other eukaryotes, as established earlier, and, thus, the YYYYYRRRRR repeat can be considered as consensus nucleosome DNA sequence repeat across eukaryotic species. Similar distance analysis for [A, T] dinucleotides suggested the related pattern (TTTYTARAAA)n where the TT and AA dinucleotides display rather out of phase behavior, contrary to the "AA or TT" in-phase periodicity, considered in some publications. A weak 5-base periodicity in the distribution of TA dinucleotides was detected.
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Base de dados:
MEDLINE
Assunto principal:
Nucleossomos
/
Sequências Repetitivas de Ácido Nucleico
/
Análise de Sequência de DNA
/
Caenorhabditis elegans
Limite:
Animals
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article