The Rex proteins of human T-cell leukemia virus type II differ by serine phosphorylation.
J Virol
; 65(1): 546-50, 1991 Jan.
Article
em En
| MEDLINE
| ID: mdl-1898667
ABSTRACT
The Rex proteins of human T-cell leukemia virus types I and II (HTLV-I and HTLV-II) induce cytoplasmic expression of unspliced gag-pol mRNA and singly spliced env mRNA and are critical for virus replication. Two rex gene products, p27rex and p21rex of HTLV-I and p26rex and p24rex of HTLV-II, have been detected in HTLV-infected cells; however, the structural and biological relationship of the proteins has not been clearly elucidated. Endoproteinase digestion and phosphoamino acid analysis of HTLV-II Rex indicated that p24rex has the same amino acid backbone as p26rex and that the larger apparent molecular size of p26rex is attributable to serine phosphorylation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Serina
/
Vírus Linfotrópico T Tipo 2 Humano
/
Produtos do Gene rex
Limite:
Animals
Idioma:
En
Ano de publicação:
1991
Tipo de documento:
Article