Epithelial stem/progenitor cells in lung postnatal growth, maintenance, and repair.
Cold Spring Harb Symp Quant Biol
; 73: 291-5, 2008.
Article
em En
| MEDLINE
| ID: mdl-19028985
ABSTRACT
The adult lung consists of a trachea leading into a system of branched airways ending in millions of alveolar sacs. It contains many different epithelial cell types arranged in precise patterns along the proximodistal axis. Each region of the lung has the capacity to repair through the proliferation of different epithelial cell types. However, the precise identity of the cells mediating repair is not fully resolved. To address this problem, we are using genetic lineage-labeling techniques in the mouse. The tools we have made will also be useful for understanding how progenitor cell behavior is regulated under normal and pathological conditions.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Células-Tronco Adultas
/
Pulmão
Limite:
Animals
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article