Annulations of enantioenriched allenylsilanes with in situ generated iminium ions: stereoselective synthesis of diverse heterocycles.
Org Lett
; 11(2): 473-6, 2009 Jan 15.
Article
em En
| MEDLINE
| ID: mdl-19072097
ABSTRACT
Highly enantioenriched allenylsilanes participate in Lewis acid mediated annulations with in situ generated iminium ions derived from tert-butyl carbamate and methyl carbamate to selectively form functionalized 4,5-dihydropyrroles and 4,5-dihyrooxazines, respectively. The dihydropyrrole products were further elaborated in a stereocontrolled vinylsilane terminated cyclization with in situ generated oxonium ions, resulting in pyranopyrroles.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Silanos
/
Compostos Heterocíclicos
/
Iminas
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article