Red blood cell alloimmunization complicating plasma transfusion.
Am J Clin Pathol
; 96(2): 201-2, 1991 Aug.
Article
em En
| MEDLINE
| ID: mdl-1907429
ABSTRACT
Well-known adverse effects of plasma transfusion include viral transmission, allergic complications, and rare anaphylactic reactions. In making clinical decisions to transfuse plasma, a seldom-considered complication is that of red blood cell (RBC) alloimmunization. The authors report a patient in whom strong IgM and IgG anti-E and weak IgG anti-JKa RBC antibodies developed 15 days after infusion of two units of fresh-frozen plasma for volume expansion. These antibodies are potentially hemolytic. This case underscores the importance of considering risks of plasma infusion. Plasma should not be used casually, especially for indications for which alternate therapies, such as crystalloid and colloid solutions, are available.
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Base de dados:
MEDLINE
Assunto principal:
Imunização
/
Eritrócitos
/
Reação Transfusional
/
Isoanticorpos
Tipo de estudo:
Prognostic_studies
Limite:
Aged
/
Female
/
Humans
Idioma:
En
Ano de publicação:
1991
Tipo de documento:
Article