Structure-activity relationship of flavonoids active against lard oil oxidation based on quantum chemical analysis.
Molecules
; 14(1): 46-52, 2008 Dec 23.
Article
em En
| MEDLINE
| ID: mdl-19104485
ABSTRACT
In this study, the antioxidant activities of 15 flavonoids against lard oil oxidation were determined by using the Rancimat test. Quercetin, dihydromyricetin, luteolin and kaempferol showed the strongest antioxidant activity, with protection factor values (PF) of 11.50, 11.29, 4.24 and 2.49, respectively. The role of conjugated hydroxyl groups of the B and C ring is discussed. By using the following descriptors DeltaH(f) (the difference in heat of formation between flavonoids and their free radicals resulted after hydrogen atom donation) and H(BC) (the number of conjugated hydroxyl groups of the B and C ring), the result obtained in the antioxidant Rancimat test could be successfully explained.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Flavonoides
/
Óleos
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Gorduras na Dieta
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Antioxidantes
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article