Search for serum biomarkers associated with abdominal aortic aneurysm growth--a pilot study.
Eur J Vasc Endovasc Surg
; 37(3): 297-9, 2009 Mar.
Article
em En
| MEDLINE
| ID: mdl-19111482
ABSTRACT
INTRODUCTION:
Serological biomarkers could reflect asymptomatic infrarenal aortic aneurysm (AAA) activity and guide patient management. REPORT Serum concentrations of C-reactive protein (CRP), alpha 1-antitrypsin and lipoprotein(a) were measured in blood samples from 35 AAA patients and 35 controls and correlated with the aortic diameter and AAA growth in the previous 12 months. We found a positive correlation between CRP and AAA diameter (r=0.46; p=0.007) and alpha 1-antitrypsin and AAA growth (r=0.55; p=0.004).CONCLUSIONS:
Alpha 1-antitrypsin may be a promising biomarker of AAA growth.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Proteína C-Reativa
/
Alfa 1-Antitripsina
/
Lipoproteína(a)
/
Aneurisma da Aorta Abdominal
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article