Genetics of atrial fibrillation.
Cardiol Clin
; 27(1): 25-33, vii, 2009 Feb.
Article
em En
| MEDLINE
| ID: mdl-19111761
ABSTRACT
Recent studies of AF have identified mutations in a series of ion channels; however, these mutations appear to be relatively rare causes of AF. A genome-wide association study has identified novel variants on chromosome 4 associated with AF, although the mechanism of action for these variants remains unknown. Ultimately, a greater understanding of the genetics of AF should yield insights into novel pathways, therapeutic targets, and diagnostic testing for this common arrhythmia.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fibrilação Atrial
/
Predisposição Genética para Doença
Limite:
Humans
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article